LINUS October 1996

CD-ROM Highlights

SEDBASE

Betty Lam, Medical Library

SEDBASE is the CD-ROM equivalent of Meyler's Side Effects of Drugs and Side effects of Drugs Annual. Published annually, it contains articles on the clinically relevant side effects and interactions of all drugs currently in use. Topics covered include adverse drug reactions, drug interactions, pharmacological or patient-dependent factors associated with the occurrence of side effects and special risk situations.

You can conduct the following searches:

  1. Find a term occurring anywhere in the database
  2. Find a specific drug with a specific effect
  3. List a summary of reactions & risks for a specific drug
  4. What are the side effects of a specific drug
  5. What are the interactions between specific drugs
  6. What drugs cause a specific side effect
  7. What drugs interact with a specific drug
  8. What drug combinations cause a specific side effect

Sample record from SEDBASE

E.g. Search for Aspirin

Brief format (Citn) :

EFCT: diuresis (E16-09)

DRG1: Caffeine (D01-01-01)

FACT: High-dose

Full format :

EFCT: diuresis (E16-09)

EFF: Water-excretion

DRG1: Caffeine (D01-01-01)

DRUG: Caffeine; guaranine; guarin; thein; 1,3,7-trimethy-1H-purine-2, 6-dione.

FACT: high-dose

TXOO: Caffeine. Urinary system. Large doses of Caffeine may cause diuresis. Administration of Caffeine citrate daily increased the Mean urinary excretion rate...The nephrotoxity of analgesic/antipyretic drug interaction may be the result of a combined effect in which Aspirin, Phenacetin and Caffeine all play a role...

Note that each record contains the following fields:

EFF Contains the following two fields:
EFCT Effect name, classification code and, for some records, the condition(s) under which the side effect may occur.
SYN Synonyms for effect
DRUG Contains the following four fields:
DRG1 Drug name and classification code
SYN1 Synonyms for drug
DRG2 Interacting drug name and classification code
SYN2 Synonyms for interacting drug
CROS Cross reference to another drug name
FACT Factors of influence
TXT Text from Meyler's, the Annual, and preliminary reviews
REFERENCE Bibliographic reference
SUBJ Subject of record
DOC Document number (a limit field)

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LINUS October 1996, The National University of Singapore Library